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T-cell lymphomas



 

T-Cell Lymphoma

There are many types of T-cell lymphoma, just as there are many B-cell types of lymphoma. Although this page appears grouped with the other aggressive forms of NHL there are also indolent T-cell types so if you don't see your type here, look in the indolent lymphoma section. This page is simply a collection of authoritative articles about many types of T-cell lymphoma and no one type in specific. Our Advanced Search page lets you perform a focused search of a specific type from prestigious medical journals.

There is still no consensus about whether T-cell lymphomas respond as well to treatment as their corresponding B-cell types. Most experts will agree that they remain a challenge to treat.

Here are some excellent articles that discuss T-cell lymphomas in-depth.

This first link is to a webcast from Jasmine Zain, MD Columbia University Medical Center, New York.(Approx 45 minutes long)

How I treat T-Cell lymphomas

Next we have The CancerNetworks latest series about T-cell lymphomas.

Peripheral T-cell lymphomas: Their time has come

Next we have Grand Rounds in Hematology newsletter from Bloodline.

Click here to read the newsletter

Topics covered in the above newsletter include:

  • Introduction
  • Update on the Pathophysiology of T-cell Lymphomas
  • Therapeutic options for patients with Peripheral T-cell lymphoma
  • Clinical Vignettes in Cutaneous T-Cell Lymphoma: Practical Applications for Emerging Data on Mycosis Fungoides/Sézary Syndrome
  • What's new in Gastric MALT lymphoma
  • Primary  Central Nervous System Lymphoma.

The Cancer network's T-cell lymphoma series.

Primary Cutaneous and Systemic Anaplastic Large Cell Lymphoma

From the prestigious journal Blood, this next link is a thorough review of all the peripheral T-cell lymphomas. It discusses their pathology and biology, what the prognosis is for the various types, and current and new treatment strategies. It is a must read for anyone wishing to learn about peripheral T-cell lymphoma.

Peripheral T-cell lymphoma from the Journal Blood

Next is a review of the status of using stem cell transplants in the treatment of T-cell lymphoma, from the journal, Annals of Oncology.

Stem-cell transplantation in T-cell non-Hodgkin’s lymphomas

The following is from Blood journal.

Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma

Below is an article from the ASH education series that reviews the biology, prognosis and treatment options for T-cell lymphomas, with an emphasis on peripheral T-cell types.

ASH education review of T-cell lymphomas

The following article from the Blood Journal explores how the type of skin erruption is a prognostic factor in cutaneous Adult T-cell Lymphoma/Leukaemia

Type of skin eruption is an independent prognostic indicator for adult T-cell leukemia/lymphoma

Another important new treatment is Pralatrexate. The recently published PROPEL clinical trial showed a 27% response rate in patients with relapsed or refractory Peripheral T-cell lymphoma. Click the link below to read the study.

Pralatrexate in patients with relapsed or refractory peripheral T-cell lymphoma: results from the pivotal PROPEL study.